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Reduction of metastases of Lewis lung carcinoma by an ayurvedic food supplement (MAK-4) in mice 60caps ashwagandha otc anxiety facts. Ayurvedic (science of life) agents induce differentiation in murine neuroblastoma cells in culture cheap ashwagandha 60 caps with amex anxiety shortness of breath. Antioxidant adjuvant therapy using natural herbal mixtures (MAK-4 and MAK-5) during intensive chemotherapy: reduction in toxicity. The doshas and their functioning in terms of contemporary biology and physical chemistry. Human Physiology: Expression of Veda and Vedic Literature : Modern Science and Ancient Vedic Science Discover the Fabrics of Immor-tality in Human Physiology, 4th edn. A double blind randomized controlled trial of Maharishi Vedic vibration technology in subjects with arthritis. Maharishi Vedic vibration technology on chronic disorders and associated quality of life. Lipophil-mediated reduction of toxicants in humans: an evaluation of an ayurvedic detoxification procedure. The impact of the transcendental meditation program on government payments to physicians in Quebec: an update. Improvements in chronic diseases with a comprehensive natural medicine approach: a review and case series. Effect of a multimodality natural medicine program on carotid atherosclerosis in older subjects: a pilot trial of Maharishi Vedic Medicine. Three randomized experiments on the longitudinal effects of the Transcendental Meditation technique on cognition. Transcendence and psychological health: studies with long-term participants of the transcendental meditation and TM-Sidhi program. The effects of the transcendental mediation technique and progressive muscle relaxation on EEG coherence, stress reactivity, and mental health in black adults. Electrophysiological correlates of higher states of consciousness during sleep in long-term practitioners of the Transcendental Meditation program. Cortical plasticity, contingent negative variation, and transcendent experiences during practice of the Transcendental Meditation technique. Biol Psychol 2000; 55:41–55 9 Hatha yoga and meditation for neurological conditions David Riley Complementary Therapies in Neurology: An Evidence-Based Approach Edited by Barry S. Oken ISBN 1-84214-200-3 Copyright © 2004 by The Parthenon Publishing Group, London INTRODUCTION Hatha yoga and meditation have become increasingly popular in our culture today. The Yoga Journal has estimated that almost 15 million people attend or have attended a yoga class and an equal number have tried one form of meditation or another. As these two interconnected disciplines move from their roots as a spiritual practice for personal growth to techniques with potential medical applications, it is worthwhile to evaluate potential mechanisms of action, the evidence for their effectiveness and whether or not they might hold promise in treating patients. HATHA YOGA: HISTORY AND THEORY The potential medical applications of Hatha yoga in the treatment of neurological conditions are linked, in the absence of a clearly defined mechanism of action, to several related hypotheses. One hypothesis is that the postures of Hatha yoga, when integrated with the attention to the breath known as pranayama and practiced in a state of focused or meditative awareness, can modulate or reset the resting tone of the autonomic nervous system either directly or through a modulation of the neuroendocrine system and related neurotransmitters. There are likely to be many more peripheral events that occur in the nervous or musculoskeletal systems that can be measured involving the intrafusal and golgi tendon-organ feedback loops when flexion and extension systems are activated sequentially during the practice of Hatha yoga. Long-time practitioners of Hatha yoga and pranayama have a remarkably sophisticated belief about the motion of the central nervous system during different phases of respiration and this is shared with some doctors of osteopathy. The neuroendocrine-immune system and the autonomic nervous system are felt to be influenced by the motion of the structures of the central nervous system. This motion can be modulated by practitioners of yoga during the practice of Hatha yoga, pranayama and meditation in a similar fashion to other complementary therapies such as some applications of osteopathy. Complementary therapies in neurology 190 States of autonomic nervous system imbalance are believed to have a unique relationship to a wide variety of disease processes. Today we live in a society that is infused with a high level of sympathetic nervous system stimulation resulting in an abnormally elevated sympathetic tone.

Tea tree Antiseptic and soothing Common cold buy ashwagandha 60caps overnight delivery anxiety symptoms not going away, bronchitis order ashwagandha 60 caps without a prescription anxiety girl, abscesses, acne, vaginitis, and burns. Thyme Stimulant, antiseptic, antibacterial, Cough, laryngitis, diarrhea, gas, and intestinal worms. He wrote about and irregularities, stress-related conditions, mood dis- his use of essential oils and their healing and antiseptic orders, circulatory problems, respiratory infections, properties, in his 1964 book Aromatherapie, traitement and wounds. Later, French bio- chemist Mauguerite Maury popularized the cosmetic In aromatherapy, essential oils are carefully selected benefits of essential oils, and in 1977 Robert Tisserand for their medicinal properties. As essential oils are ab- wrote the first English language book on the subject, The sorbed into the bloodstream through application to the Art of Aromatherapy, which introduced massage as an skin or inhalation, their active components trigger cer- adjunct treatment to aromatherapy and sparked its popu- tain pharmalogical effects (e. The volatility of an oil, or Benefits the speed at which it evaporates in open air, is thought to be linked to its specific psychological effect. As a rule of Aromatherapy offers diverse physical and psycho- thumb, oils that evaporate quickly are considered emo- logical benefits, depending on the essential oil or oil tionally uplifting, while slowly-evaporating oils are combination and method of application used. An anti- tial oils are used to treat a wide range of symptoms inflammatory and analgesic. Useful in treating otitis and conditions, including, but not limited to, gastroin- media (earache), skin conditions, menstrual pains, and testinal discomfort, skin conditions, menstrual pain depression. GALE ENCYCLOPEDIA OF ALTERNATIVE MEDICINE 2 123 Limbic system of the brain Olfactory bulb Nasal cavity Aromatic substances Olfactory neurons As a holistic therapy, aromatherapy is believed to benefit both the mind and body. Here, the aromatic substances from a flower stimulates the olfactory bulb and neurons. The desired emotional response (such as relaxation) is activated from the limbic system of the brain. Citrus oil not only used to treat oily hair and skin, but is also said extracted from bitter orange flower and peel and used to be useful in regulating the menstrual cycle, improv- to treat sore throat, insomnia, and stress and anxiety- ing mood, and controlling high blood pressure. An essential oil used to treat stomach complaints and known for its reported • Lavender (Lavandula officinalis). Relaxes and soothes the cations, including treatment of insect bites, burns, res- stomach muscles and gastrointestinal tract. In addition, re- search in 2002 found that peppermint scent helped ath- • Myrtle (Myrtus communis). Myrtle is a fungicide, dis- letes run faster and perform more push–ups than control infectant, and antibacterial. Brain scans have shown that fra- oil used and the therapeutic use of the application may also grance of rosemary increases blood circulation in the brain. Individuals should seek guidance from a healthcare professional and/or aro- • Tea tree (Melaleuca alternifolia). Rec- Massage is a common therapeutic technique used in ommended for treating sore throat and respiratory in- conjunction with aromatherapy to both relax the body and fections, vaginal and bladder infections, wounds, and a thoroughly administer the essential oil treatment. As a sore throat remedy, antiseptic and soothing sometimes used to treat hypertension and tachycardia. While some basic aromatherapy home treatments can be self-administered, medical aro- Internal use matherapy should always be performed under the guid- ance of an aromatherapist, herbalist, massage therapist, Some essential oils can be administered internally in nurse, or physician. Essential oils should only be Inhalation taken internally under the supervision of a qualified The most basic method of administering aromather- healthcare professional. Sev- As non-prescription botanical preparations, the es- eral drops of an essential oil can be applied to a tissue or sential oils used in aromatherapy are typically not paid handkerchief and gently inhaled. The self-administered nature of sential oil can also be added to a bowl of hot water and the therapy controls costs to some degree. This technique is recommend- treatment sessions from a professional aromatherapist ed when aromatherapy is used to treat respiratory and/or are not covered by health insurance in most cases, al- skin conditions. Aromatherapy steam devices are also though aromatherapy performed in conjunction with available commercially. A warm bath containing essen- physical therapy, nursing, therapeutic massage, or other tial oils can have the same effect as steam aromatherapy, covered medical services may be covered. When should check with their insurance provider to find out used in a bath, water should be lukewarm rather than hot about their specific coverage.

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Over the centuries 60caps ashwagandha visa anxiety symptoms pain in chest, onion has been used for healing both internally and externally order 60 caps ashwagandha otc anxiety symptoms 24 hours day. Internally, onion has been Modern scientific research supports many of the tra- recommended to treat colds, cough, bronchitis, whoop- ditional uses for onion. Onion contains thiosulphinate, a ing cough, asthma, and other respiratory problems. It is compound that is effective in killing many common bac- believed to help loosen congestion in the lungs and ex- teria, including Salmonella typhi, Pseudomonas aerigi- pand the airways. This finding supports the folk use of onion to treat wounds and skin infections and Onion is also used internally to relieve excess gas and possibly its use for an upset stomach. A mixture of rue (Ruta graveolens) and onion is used to rid the digestive system of parasites. Even more supportive are small clinical studies on Onion is also thought to stimulate the appetite. It is also thought to help reduce arteriosclerosis only a small number of people, they are consistently sup- by lowering blood cholesterol levels and preventing the ported by additional data from animal and test-tube stud- GALE ENCYCLOPEDIA OF ALTERNATIVE MEDICINE 2 59 ies. In 1990, scientists detected the presence of a com- pound in onion that partially blocks the development of in- Antioxidant—An enzyme or other organic sub- flammation. In addition, laboratory animals were protected stance that is capable of counteracting the damag- against induced asthma with fresh onion juice. Onion has with asthma have also shown reduced allergy-induced con- been found to contain antioxidants. Diuretic—Any substance that increases the pro- These findings support the traditional folk administration duction of urine. Tincture—An alcohol-based extract prepared by Some test-tube and small animal studies suggest that soaking plant parts. Whether these results are applicable to humans remains to be seen, but in a 1989 study done in China, people who ate large amounts of vegetables in the Allium family appeared to Interactions have a significantly reduced rate of stomach cancer. There are no studies of the interaction of onion and Onion has also been shown to contain antioxidants, conventional pharmaceuticals. However, given the long which are compounds that protect the body against free and widespread use of onion as a vegetable, serious in- radicals. Lon- uate scientific literature and case studies pertaining to don: Dorling Kindersley, 1996. In general, however, it Practical Guide to Natural Medicines New York: William appears that onion is a healthful vegetable that may con- Morrow and Company, 1999. A recent study of the antioxidant activity of onion juice indicates that it is not affected by Tish Davidson heating or boiling. A common dose is 1/4–1 cup of raw onions daily or one teaspoon of juice three times a day. Allium sativa see Garlic Precautions No special precautions are needed when taking onion medicinally. Aloe Side effects Description Although no allergic reactions to the bulb of the onion Appearance are reported, some people develop an allergic rash after han- dling the leaves of the plant. In addition, windblown parti- Aloe vera, a member of the lily family, is a spiky, cles of onion leaves and skin have been shown to irritate the succulent, perennial plant. It is indigenous to eastern and eyes of farm workers employed to harvest the onions. There are about 300 identified species, but Aloe vera (“true aloe”) is the most popular for med- ical applications. The plant has yellow flowers and triangular, fleshy leaves with serrated edges that arise from a central base and may grow to nearly 2 ft (0. A clear gel, that is the part of the plant used for topical application is contained within the cells of the generous inner portion. Anthraquinones, which exert a marked laxative effect, are contained in the bitter yellow sap of the middle leaf layer. The Use of the plant is thought to have originated in Egypt latest, and perhaps most exciting component discovered or the Middle East.

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Mild transient hypoglycemia or hyper- glycemia may result from alterations in insulin ashwagandha 60 caps mastercard anxiety 9 year old, Flutamide glucagon buy ashwagandha 60 caps amex anxiety symptoms social, or growth hormone secretion. Flutamide (Eulexin) is a nonsteroidal antiandrogen (see Chapter 63) compound that competes with testosterone MISCELLANEOUS AGENTS for binding to androgen receptors. It is an active agent in Hydroxyurea the hormonal therapy of cancer of the prostate and has been shown to complement the pharmacological castra- Hydroxyurea (Hydrea) inhibits the enzyme ribonu- tion produced by the gonadotropin-releasing hormone cleotide reductase and thus depletes intracellular pools (GnRH) agonist leuprolide. Flutamide prevents the of deoxyribonucleotides, resulting in a specific impair- stimulation of tumor growth that may occur as a result ment of DNA synthesis. The drug therefore is an S- of the transient increase in testosterone secretion after phase specific agent whose action results in an accumu- the initiation of leuprolide therapy. The most common lation of cells in the late G1- and early S-phases of the side effects of flutamide are those expected with andro- cell cycle. Hydroxyurea is rapidly absorbed after oral adminis- Mild nausea and diarrhea occur in about 10% of pa- tration, with peak plasma levels achieved approxi- tients. The primary route of ex- Procarbazine may potentiate the effects of tranquil- cretion is renal, with 30 to 40% of a dose excreted un- izers and hypnotics. Only a small percentage of pa- Mitotane tients with other malignancies have had even brief re- missions induced by hydroxyurea administration. The observation that mitotane (Lysodren) could pro- Hematological toxicity, with white blood cells af- duce adrenocortical necrosis in animals led to its use in fected more than platelets, may occur. Megaloblastosis the palliation of inoperable adrenocortical adenocarci- of the bone marrow also may be observed. A reduction in both tumor size and adrenocorti- rapid, generally within 10 to 14 days after discontinua- cal hormone secretion can be achieved in about half of tion of the drug. Because normal adreno- pigmentation and hyperkeratosis, have been reported cortical cells also are affected, endogenous glucocorti- with chronic treatment. Mitotane is incompletely absorbed from the gas- Procarbazine trointestinal tract after oral administration. However, Procarbazine (Matulane) may autooxidize sponta- once absorbed, it tends to accumulate in adipose tissue. The major toxicities associated with its reactive products may degrade DNA and serve as one use are anorexia, nausea, diarrhea, lethargy, somno- mechanism of procarbazine-induced cytotoxicity. Procarbazine is rapidly absorbed after oral adminis- Although both DNA and RNA synthesis are inhibited tration and has a plasma half-life of only 10 minutes. Urinary excre- administration, with peak plasma levels achieved after 1 tion accounts for 70% of the procarbazine and its hour. The drug is readily metabolized to form a number metabolites lost during the first 24 hours after drug ad- of demethylated metabolites. It also has some activity mechlorethamine, vincristine, and prednisone in the against small cell lung cancer. Procarbazine is also used in suppression and a peripheral neuropathy also may various combination chemotherapy protocols for non- occur. Limited antitumor effects Cisplatin have been observed against multiple myeloma, melanoma, and non–oat cell lung cancers. Cisplatin (Platinol) is an inorganic coordination com- The major side effects associated with procarbazine plex with a broad range of antitumor activity. It is espe- therapy are nausea and vomiting, leukopenia, and throm- cially useful in the treatment of testicular and ovarian bocytopenia. Procar- N7 and O6 of guanine, producing alterations in DNA bazine administration produces a high degree of chro- structure and inhibition of DNA synthesis. Adjacent mosomal breakage, and the compound is mutagenic, ter- guanine residues on the same DNA strand are preferen- atogenic, and carcinogenic in experimental systems. This platinating activity is analogous 652 VI CHEMOTHERAPY to the mode of action of alkylating agents. Cisplatin also orubicin in multidrug-resistant cells and in patients who binds extensively to proteins. Mitoxantrone is active against breast carcinomas, Cisplatin shows biphasic plasma decay with a distri- leukemias, and lymphomas. Its antitumor efficacy in pa- bution phase half-life of 25 to 49 minutes and an elimi- tients with breast cancer is slightly lower than that of nation half-life of 2 to 4 days. Its major toxicity is myelosuppression; mu- drug is bound to plasma proteins, and binding may ap- cositis and diarrhea also may occur.

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